Penn Herb Wellness Guide
Hyaluronic AcidFind Products
Hyaluronic acid is a member of the family of molecules known as glycosaminoglycans. This family also includes chondroitin sulfate and some other large carbohydrate-containing molecules. Hyaluronic acid is an important component of the connective tissue that fills the spaces between cells of the skin and other tissues, and is a major ingredient of the synovial fluid that lubricates and cushions joints as well as the vitreous humor that fills the inner chamber of the eye.1
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement,little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:
| Used for | Amount | Why |
|---|---|---|
Gingivitis | Apply five times per day for one week or twice per day for three weeks |  [2 stars] Gels and sprays containing hyaluronic acid, an important connective tissue component in the gums, have been shown to help reduce bleeding tendency and other indicators of gingivitis. |
Skin Ulcers | Apply a gel containing a partial benzyl ester derivative of hyaluronan under compression bandaging daily | [2 stars] A trial found that topical application of a hyaluronic acid compound with compression bandaging was significantly better than bandaging alone for healing chronic venous skin ulcers. |
Wound Healing | 1% solution for ears | [2 stars] Topically applied hyaluronic acid is sometimes used in skin wound dressings to improve healing. |
Osteoarthritis | Refer to label instructions |  [1 star] Injection of hyaluronic acid compounds into osteoarthritic joints, primarily the knee, has been shown to improve symptoms. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.