Penn Herb Wellness Guide
Chondroitin SulfateFind Products
Chondroitin sulfate consists of repeating chains of molecules called glycosaminoglycans (GAGs). Chondroitin sulfate is a major constituent of cartilage, providing structure, holding water and nutrients, and allowing other molecules to move through cartilage—an important property, as there is no blood supply to cartilage.
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement,little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:
| Used for | Amount | Why |
|---|---|---|
Osteoarthritis | 800 to 1,200 mg a day |  [3 stars] Many trials have shown that supplementing with chondroitin sulfate reduces pain, increases joint mobility, and promotes healing within the joints. |
High Cholesterol | 500 mg three times daily |  [2 stars] Chondroitin sulfate appears to sequester cholesterol, lowering circulating cholesterol levels and reducing atherosclerosis. |
Wound Healing | Refer to label instructions | as Chondroitin Sulfate Topical[2 stars] Applying an ointment containing chondroitin sulfate may speed healing of skin wounds. |
Atherosclerosis | Refer to label instructions |  [1 star] Preliminary research shows that chondroitin sulfate may prevent atherosclerosis and may also prevent heart attacks in people who already have atherosclerosis. |
Heart Attack | Refer to label instructions | [1 star] Taking chondroitin sulfate may reduce the risk of heart attack in people with a history of heart disease or who are at risk for heart attack. |
Kidney Stones | Refer to label instructions | [1 star] Chondroitin sulfate may help reduce the risk of kidney stone formation. One trial found that glycosamionoglycans significantly lowered urinary oxalate levels, which reduces the risk of stone formation. |
Sprains and Strains | Refer to label instructions | [1 star] Chondroitin sulfate may promote wound healing by providing the raw material needed by the body to manufacture molecules found in skin, tendons, ligaments, and joints. |
Wound Healing | Refer to label instructions | as Chondroitin Sulfate Oral[1 star] Supplementing with chondroitin sulfate may promote wound healing by providing the raw material needed by the body to manufacture connective tissue. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.