Penn Herb Wellness Guide
Alpha Lipoic AcidFind Products
Alpha lipoic acid (ALA) is a vitamin-like antioxidant, sometimes referred to as the “universal antioxidant” because it is soluble in both fat and water.1 ALA is manufactured in the body and is found in some foods, particularly liver and yeast.
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement,little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:
| Used for | Amount | Why |
|---|---|---|
Obesity | 600 mg one to three times per day |  [3 stars] Multiple clinical trials have found alpha-lipoic acid can slightly decrease body weight and may reduce waist circumference in people with abdominal obesity. |
Type 1 Diabetes | 600 to 1,200 mg daily | [3 stars] Supplementing with alpha-lipoic acid may improve the symptoms of diabetic nerve damage (neuropathy). |
Type 2 Diabetes | 600 to 1,200 mg daily | [3 stars] Taking alpha lipoic acid may improve insulin sensitivity and help protect against diabetic complications such as nerve damage. |
Migraine Headache | 600 mg per day |  [2 stars] In a small double-blind trial, supplementing with alpha-lipoic acid significantly reduced the frequency of migraine attacks. |
Neuropathy | 600 to 1,200 mg daily | [2 stars] Alpha-lipoic acid may reduce symptoms of diabetic peripheral neuropathy and may work best in combination with medical treatment for neuropathy. Its possible benefit in chemotherapy-induced neuropathy needs further investigation. |
Vitiligo | Refer to label instructions | [2 stars] In one study, supplementing with a combination of antioxidants including alpha-lipoic acid increased the effectiveness of ultraviolet light therapy.
|
Glaucoma | Refer to label instructions |  [1 star] Alpha lipoic acid may improve visual function in people with some types of glaucoma. |
Hepatitis | Refer to label instructions | [1 star] In one trial, a combination of alpha lipoic acid, silymarin, and selenium led to significant improvements in liver function and overall health in people with hepatitis C. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.