Penn Herb Wellness Guide
Acetyl-L-CarnitineFind Products
Acetyl-L-carnitine is similar in form to the amino acid L-carnitine and also has some similar functions, such as being involved in the metabolism of food into energy. The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement,little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:
| Used for | Amount | Why |
|---|---|---|
Age-Related Cognitive Decline | 1,500 mg daily |  [3 stars] Several clinical trials suggest that this supplement delays onset of ARCD and improves overall cognitive function in the elderly |
Neuropathy | 500 to 1,000 mg three times daily | [3 stars] Taking acetyl-L-carnitine can reduce pain in people with diabetic neuropathy, but does not appear to consistently benefit cases of chemotherapy-induced neuropathy. |
Alzheimer’s Disease | 1 gram taken three times per day |  [2 stars] Short-term studies have found that people with Alzheimer’s disease who supplement with acetyl-L-carnitine experience improved memory, enhanced overall performance, and delayed disease progression. |
Depression | Refer to label instructions | [2 stars] Acetyl-L-carnitine has been shown in several studies to significantly reduce depression symptoms in seniors. |
Down Syndrome | 500 mg three times per day | [2 stars] Acetyl-L-carnitine appears to improve visual memory and attention in people with Down syndrome. |
Erectile Dysfunction (L-Carnitine) | 2 grams of each daily | [2 stars] In one study, supplementing with the combination of propionyl-L-carnitine (a form of L-carnitine) and acetyl-L-carnitine significantly improved erectile function in elderly men. |
Fibromyalgia | 1,500 mg daily for ten weeks | [2 stars] Supplementing with acetyl-L-carnitine may improve musculoskeletal pain, depression, and general health in people with fibromyalgia.
|
Liver Cirrhosis | 2 grams twice a day for 3 months | [2 stars] A double-blind trial suggests that supplementing with acety-l-carnitine mayimprove mental and neurological function in peoplewhose cirrhosis has impaired function.
|
Macular Degeneration (Coenzyme Q10, Fish Oil) | Follow label directions | [2 stars] In one study, supplementing with a proprietary blend of acetyl-L-carnitine, fish oil, and coenzyme Q10 improved visual function in people with macular degeneration. |
Type 1 Diabetes and Diabetic Neuropathy | 500 to 1,000 mg three times daily | [2 stars] Taking acetyl-L-carnitine may improve symptoms of diabetic neuropathy. |
Type 2 Diabetes and Diabetic Neuropathy | 500 to 1,000 mg three times daily | [2 stars] Taking acetyl-L-carnitine may improve symptoms of diabetic neuropathy. |
Amenorrhea | Refer to label instructions |  [1 star] Acetyl-L-carnitine may help restore menstruation in some amenorrheic women.
|
Male Infertility | Refer to label instructions | [1 star] Acetylcarnitine may be a useful for treatment of male infertility caused by low quantities of immobile sperm. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.