Penn Herb Wellness Guide
Raynaud’s Disease
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
| Supplement | Amount | Why |
|---|---|---|
Fish Oil | 4 grams of EPA per day |  [2 stars] Supplementing with fish oil may reduce the severity of blood-vessel spasm. |
Vitamin B3 (Niacin) | 3 to 4 grams daily of inositol hexaniacinate | [2 stars] A variation on the B vitamin niacin, inositol hexaniacinate has been shown to reduce arterial spasm and improve peripheral circulation. |
Evening Primrose Oil | Refer to label instructions |  [1 star] Fatty acids in evening primrose oil (EPO) inhibit the formation of prostaglandins, which promote blood vessel constriction. One study found that supplementing with EPO reduced the number and severity of attacks. |
Ginkgo | Refer to label instructions | [1 star] The herb Ginkgo has been reported to improve the circulation in small blood vessels and reduce pain in people with Raynaud’s disease. |
L-Carnitine | Refer to label instructions | [1 star] In one study, people with Raynaud’s disease who were given L-carnitine showed less blood-vessel spasm in their fingers in response to cold exposure. |
Magnesium | Refer to label instructions | [1 star] Abnormalities of magnesium metabolism have been reported in people with Raynaud’s disease. Magnesium deficiency results in blood-vessel spasm, which may be helped with supplementation. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.