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Penn Herb Wellness Guide

Phenylketonuria

Also indexed as:Folling’s Disease, PKU
Early diagnosis is key to treating PKU, a rare genetic disorder that results in an amino acid imbalance in the body. According to research or other evidence, the following self-care steps may be helpful.
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Early diagnosis is key to treating PKU, a rare genetic disorder that results in an amino acid imbalance in the body. According to research or other evidence, the following self-care steps may be helpful.
  • Fight back with fish oil

    Take a daily supplement containing 500 mg for every 8.8 pounds of body weight to prevent deficiencies caused by the PKU diet

  • Seek support from supplements

    Prevent vitamin and mineral deficiencies caused by the PKU diet by taking supplements that provide the daily value of L-tyrosine, vitamin K, vitamin B12, and selenium

  • Discover branched-chain amino acids

    Under a healthcare provider’s supervision, improve mental functioning by adding amino acid supplements to each meal and at bedtime; take 150 mg per 2.2 pounds (1 kg) of body weight each of valine and isoleucine, and 200 mg per 2.2 pounds (1 kg) of body weight of leucine

  • Monitor amino acids in your diet

    Work with your healthcare provider and a nutritionist to maintain a phenylalanine-restricted diet that is nutritionally adequate

  • Pass up aspartame

    Help prevent increased phenylalanine intake by steering clear of soft drinks, candy, and other foods and drinks sweetened with aspartame (Nutrasweet)

References

Copyright 2025 TraceGains, Inc. All rights reserved.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.