Penn Herb Wellness Guide
Amenorrhea
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
| Supplement | Amount | Why |
|---|---|---|
Progesterone | Consult a qualified healthcare practitioner |  [2 stars] The oral, micronized form has been shown to successfully induce normal menstrual bleeding in women with secondary amenorrhea. (Use of this natural hormone should always be supervised by a doctor.) |
Acetyl-L-Carnitine | Refer to label instructions |  [1 star] Acetyl-L-carnitine may help restore menstruation in some amenorrheic women.
|
Blue Cohosh | Refer to label instructions | [1 star] Traditional practitioners consider blue cohosh to be a uterine tonic and an agent that stimulates menstrual blood flow, and it is used as a remedy for lack of menstruation.
|
Calcium and Vitamin D (Osteoporosis) | Refer to label instructions | [1 star] Despite the lack of evidence that calcium and vitamin D supplements alone are helpful to amenorrheic women, they are still generally recommended to prevent the added burden of calcium and vitamin D deficiency from further contributing to bone loss. |
Motherwort | Refer to label instructions | [1 star] Motherwort has traditionally been thought to stimulate absent or diminished menses, though it has not been studied clinically. |
Partridge Berry | Refer to label instructions | [1 star] Partridge berry has traditionally been thought to stimulate absent or diminished menses, though it has not been studied clinically. |
Rue | Refer to label instructions | [1 star] Rue has traditionally been thought to stimulate absent or diminished menses, though it has not been studied clinically. |
Vitamin B6 | Refer to label instructions | [1 star] Preliminary evidence found that vitamin B6 restored menstruation and normalized hormone levels in three women with amenorrhea who had high prolactin levels.
|
Vitamin C and Clomiphene | Refer to label instructions | [1 star] Vitamin C combined with the drug clomiphene, which affects female hormone levels, is more effective at stimulating ovulation in women with amenorrhea than either substance alone. |
Vitex | Refer to label instructions | [1 star] In herbal medicine, vitex, also known as chaste tree, is sometimes used to treat amenorrhea. Research suggests it may regulate hormones related to menstruation and fertility. |
Yarrow | Refer to label instructions | [1 star] Yarrow has traditionally been thought to stimulate absent or diminished menses, though it has not been studied clinically. |
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.