Navigation

Penn Herb Wellness Guide

Acetaminophen with Codeine

Common brand names:

Aceta-codeine, Capital with codeine, Tylenol-codeine

This drug combines two primary active ingredients: acetaminophen and codeine.

Acetaminophen is used to reduce pain and fever. Unlike NSAIDs (nonsteroidal anti-inflammatory drugs), it lacks anti-inflammatory activity. Acetaminophen is available by itself or in nonprescription and prescription-only combination products used to relieve pain and the symptoms associated with colds and flu.

Codeine is a narcotic analgesic (pain reliever) derived from opium. It is used alone and in combination products to treat mild to moderate pain and as a cough suppressant.

Summary of Interactions with Vitamins, Herbs, & Foods

What Are Nutrient Interactions
Types of interactions:beneficial= Beneficialadverse= Adversecheck= Check
dnicon_BeneficialReplenish Depleted Nutrients

none

dnicon_BeneficialReduce Side Effects
Fiber
N-Acetyl Cysteine
Milk Thistle
dnicon_BeneficialSupport Medicine

none

dnicon_AvoidReduces Effectiveness
Cruciferous Vegetables
Hibiscus
High-Pectin
Teas and Herbs with Tannin
dnicon_AvoidPotential Negative Interaction
N-Acetyl Cysteine
dnicon_CheckExplanation Required
Schisandra
Vitamin C
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

Copyright 2025 TraceGains, Inc. All rights reserved.

RxAnswers is a copyrighted product from TraceGains.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

There are some limitations on the information provided in “Nutrient Interactions.” Do NOT rely solely on the information in this article. Please read the disclaimer.

Learn more about TraceGains, the company.

Learn more about the authors of RxAnswers.

TraceGains and/or its suppliers make no warranties or representations as to the accuracy or completeness of this content herein or that of any organization referred or linked to within this content and will not be liable for any damages arising out of your access to or use of any information found herein or that of any organization referred to within this content.

Information expires December 2025.